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Liu, Q., Lee, S.-S., Xiong, J., Ahmadi, S., Bell, B.J., Keleş, M.F., and Wu, M.N. (2025).  A Subcircuit in the Suprachiasmatic Nucleus Generates Wakefulness.  Adv Sci 12, doi.org/10.1002/advs.202505131.

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Lee, S.-S., Liu, Q., Cheng, A.H.R., Kim, D.W., Boudreau, D.M., Mehta, A., Keleş, M.F., Fejfer, R., Palmer, I., Park, K.H., Münzberg, H., Harris, T.D., Graves, A.R., Blackshaw, S., and Wu, M.N. (2025).  Sleep Need-Dependent Plasticity of a Thalamic Circuit Promotes Homeostatic Recovery Sleep.  Science 388, doi.org/10.1126/science.adm8203.  (Perspective in Science) 

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Keleş, M.F., Sapci, A.O.B., Brody, C., Palmer, I., Mehta, A., Ahmadi, S., Le, C., Tastan, Ö., Keleş, S., and Wu, M.N. (2025).  FlyVISTA, an Integrated Machine Learning Platform for Deep Phenotyping of Sleep in Drosophila.  Science Adv 11, doi.org/10.1126/sciadv.adq8131. 

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Liu, Q., Xiong, J., Kim, D.W., Lee, S.-S., Bell, B.J., Alexandre, C., Blackshaw, S., Latremoliere, A., and Wu, M.N. (2024).  An amygdalar oscillator coordinates cellular and behavioral rhythms.  Neuron 112, 3750-3767.  (Previewed in Neuron) 

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Brown, M.P., Verma, S., Palmer, I., Zuniga, A.G., Mehta, A., Rosensweig, C., Keles, M.F., and Wu, M.N. (2024).  A subclass of evening cells promotes the switch from arousal to sleep at dusk.  Curr Biol 34, 2186-2199.  

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Han, E.*, Lee, S.-S.*, Park, K.H., Blum, I.D., Liu, Q., Mehta, A., Palmer, I., Issa, H., Han, A., Brown, M.P., Sanchez-Franco, V.M., Velasco, M., Tabuchi, M., and Wu, M.N. (2024).  Tob Regulates the Timing of Sleep Onset at Night in Drosophila. J. Neurosci 44, doi.org/10.1523. 

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Liu, Q.*, Bell, B.J.*, Kim, D.-W., Lee, S.-S., Keles, M.F., Liu, Q., Blum, I.D., Wang, A.A., Blank, E.J., Xiong, J., Bedont, J.L., Chang, A.J., Issa, H., Cohen, J.Y., Blackshaw, S., and Wu, M.N. (2023).  A Clock-Dependent Brake for Rhythmic Arousal in the Dorsomedial Hypothalamus.  Nat Commun 14, 6381.  

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Ho, M.C.W.*, Tabuchi, M.*, Xie, X., Brown, M., Luu, S., Wang, S., Kolodkin, A., Liu, S., and Wu, M.N. (2022).  Sleep Need-Dependent Changes in Functional Connectivity Facilitate Transmission of Homeostatic Sleep Drive.  Curr Biol 32, 4957-4966.  

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Bell, B.J.*, Wang, A.A.*, Kim, D.W., Xiong, J., Blackshaw, S., and Wu, M.N. (2020).  Characterization of mWAKE Expression in the Murine Brain. J Comp Neurol, doi.org/10.1002/cne.25066.

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Lee, S.S. and Wu, M.N. (2020).  Neural Circuit Mechanisms Encoding Motivational States in Drosophila.  Curr Opin Neurobiol 64, 135-142.

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Blum, I.D. and Wu, M.N. (2019).  Sleep: Slow Waves Quiet the Fly's Mind.  Curr Biol 29, R1129-R1131.

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Xie, X.,  Tabuchi, M., Corver, A., Duan, G., Wu, M.N., and Kolodkin, A. (2019).  Semaphorin-2B Regulates Sleep Circuit Formation in the Drosophila Central Brain.  Neuron 104, 322-337.  

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Liang, X., Ho, M.C.W., Zhang, Y., Li, Y., Wu, M.N., Holy, T.E., and Taghert, P. (2019).  Morning and Evening Circadian Pacemakers Independently Drive Premotor Centers via a Specific Dopamine Relay.  Neuron 102, 843-857.  

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Tabuchi, M., Monaco, J.D., Duan, G., Bell, B., Liu, S., Liu, Q., Zhang, K., and Wu, M.N. (2018).  Clock-Generated Temporal Codes Determine Synaptic Plasticity to Control Sleep.  Cell 175, 1-15.   (Previewed in Cell)

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Xie, T.*, Ho, M.C.W.*, Liu, Q., Horiuchi, W., Lin, C.-C., Task, D., Luan, H., White, B.W., Potter, C.J., and Wu, M.N. (2018).  A Genetic Toolkit for Dissecting Dopamine Circuit Function in Drosophila.  Cell Rep 23, 652-665.

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Blum, I.D., Bell, B., and Wu, M.N. (2018).  Time for Bed:  Genetic Mechanisms Mediating the Circadian Regulation of Sleep.  Trends Genet 34, 379-388. 

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Tabuchi, M. and Wu, M.N. (2018).  Sleep: Setting the 'Circadian' Alarm Clock. Curr Biol 28, R26-R28.

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Xie, X., Tabuchi, M., Brown, M.P., Mitchell, S.P., Wu, M.N., and Kolodkin, A.L. (2017).  The Laminar Organization of the Drosophila Ellipsoid Body is Semaphorin-dependent and Prevents the Formation of Ectopic Synaptic Connections. eLife 6:e25328. doi: 10.7554/eLife.25328.

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Liu, Q.*, Tabuchi, M.*, Liu, S., Kodama, L., Horiuchi, W., Daniels, J., Chiu, L., Baldoni, D., and Wu, M.N. (2017). Branch-Specific Plasticity of a Bifunctional Dopamine Circuit Encodes Protein Hunger.  Science 356, 534-539.

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Bedont, J.L., LeGates, T.A., Buhr, E., Bathini, A., Ling, J.P., Bell, B., Wu, M.N., Wong, P.C., van Gelder, R.N., Mongrain, V., Hattar, S., and Blackshaw, S. (2017).  An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks.  Curr Biol 27, 128-136.

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Liu, S.*, Liu, Q.*, Tabuchi, M., and Wu, M.N. (2016). Sleep Drive is Encoded by Neural Plastic Changes in a Dedicated Circuit. Cell 165, 1347-1360.  (Previewed in Cell) (Recommended by Faculty of 1000).  

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Tabuchi, M., Lone, S.R., Liu, S., Liu, Q., Zhang, J., Spira, A.P., and Wu, M.N. (2015). Sleep Interacts with Abeta to Modulate Intrinsic Neuronal Excitability. Curr Biol 25, 1-11.  (Previewed in Curr Biol)

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Riabinina, O., Luginbuhl, D., Marr, E., Liu, S., Wu, M.N., Luo, L., and Potter, C.J. (2015). Improved and Expanded Q-system Reagents for Genetic Manipulations. Nat Methods 12, 219-222.

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Spira, A.P., Yager, C., Brandt, J., Smith G.S., Zhou, Y., Mathur, A., Kumar, A., Brasic, J.R., Wong, D.F., and Wu, M.N. (2014). Objectively-Measured Sleep and Beta-Amyloid Burden in Older Adults: A Pilot Study. Sage Open Medicine 2: DOI: 205031214546520.

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Liu, S.*, Lamaze, A.*, Liu, Q., Tabuchi, M., Yang, Y., Fowler, M., Bharadwaj, R., Zhang, J., Bedont, J., Blackshaw, S., Lloyd, T.E., Montell, C., Sehgal, A., Koh, K.*, and Wu, M.N.* (2014).  WIDE AWAKE Mediates the Circadian Timing of Sleep Onset.  Neuron 82, 151-166.

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Spira, A.P., Gamaldo, A.A., An, Y., Wu, M.N., Simonsick, E.M., Bilgel, M., Zhou, Y., Wong, D.F., Ferrucci, L., and Resnick, S.M. (2013). Self-Reported Sleep and Beta-Amyloid Deposition in Community-Dwelling Older Adults. JAMA Neurology 70, 1537-1543.  

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Liu, Q., Liu, S., Kodama, L., Driscoll, M.R., and Wu, M.N. (2012). Two Dopaminergic Neurons Signal to the Dorsal Fan-shaped Body to Promote Wakefulness in Drosophila. Curr Biol 22, 2114-2123.  (Previewed in Curr Biol)

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Wu, M.N. and Raizen, D.R. (2011). Notch signaling: a role in sleep and stress. Curr Biol. 21, R397-R398.

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Raizen, D.R. and Wu, M.N. (2011). Genome-wide analysis of sleep disorders. Chest 139, 446-452.

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Zheng, X., Koh, K., Sowcik, M., Smith, C., Chen, D., Wu, M.N., and Sehgal, A.S. (2009). An isoform-specific mutant reveals a role of PDP1e in the circadian oscillator. J. Neurosci 29, 10920-10927.

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Wu, M.N.* (co-first author), Ho, K.*, Yue, Z., Koh, K., and Sehgal, A.S. (2009). The effects of caffeine on sleep and circadian rhythms in Drosophila require PKA signalling, but not the adenosine receptor. J. Neurosci 29, 11029-11037.

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Wu, M.N., Koh, K., Yue, Z., Joiner, W.J., and Sehgal, A.S. (2008). A genetic screen for sleep and circadian mutants reveals mechanisms underlying sleep in Drosophila. Sleep 31, 465-472.

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